Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.56 |
| ▸ | BCHE | P06276 | 3/20 | 0.54 |
| ▸ | ACHE | P22303 | 3/20 | 0.54 |
| ▸ | BACE1 | P56817 | 2/20 | 0.54 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.50 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.50 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.50 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.49 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.49 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.49 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9294215 | 0.77 | TACR1 (0.65) | MEN1POLBKMT2ASIGMAR1HRH3 | |
| SCHEMBL9294424 | 0.77 | TACR1 (0.65) | MEN1POLBKMT2ASIGMAR1HRH3 | |
| SCHEMBL9294717 | 0.77 | TACR1 (0.65) | MEN1POLBKMT2ASIGMAR1HRH3 | |
| SCHEMBL9294712 | 0.77 | TACR1 (0.65) | MEN1POLBKMT2ASIGMAR1HRH3 | |
| SCHEMBL9294213 | 0.77 | TACR1 (0.65) | MEN1POLBKMT2ASIGMAR1HRH3 | |
| SCHEMBL9294212 | 0.77 | TACR1 (0.65) | MEN1POLBKMT2ASIGMAR1HRH3 | |
| SCHEMBL9294721 | 0.77 | TACR1 (0.65) | MEN1POLBKMT2ASIGMAR1HRH3 | |
| SCHEMBL9294438 | 0.77 | TACR1 (0.65) | MEN1POLBKMT2ASIGMAR1HRH3 | |
| SCHEMBL9294428 | 0.77 | TACR1 (0.65) | MEN1POLBKMT2ASIGMAR1HRH3 | |
| SCHEMBL3692137 | 0.73 | MEN1 (0.49) | MEN1POLBKMT2ASIGMAR1BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991009844-A1 | SUBSTANCE P ANTAGONISTS | PFIZER INC. (US) | 1991-07-11 | — | — | WO | disclosed |