Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 9/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CTSL | P07711 | 1/20 | 0.37 |
| ▸ | CTSB | P07858 | 1/20 | 0.37 |
| ▸ | CTSS | P25774 | 1/20 | 0.37 |
| ▸ | ECE1 | P42892 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5925056 | 1.00 | MME (0.49) | MMEALDH1A1CTSLCTSBCTSS | |
| SCHEMBL5796118 | 0.99 | MME (0.48) | MMEALDH1A1CTSLCTSBCTSS | |
| SCHEMBL9337016 | 0.88 | MME (0.52) | MMEALDH1A1 | |
| SCHEMBL6430188 | 0.88 | MME (0.52) | MMEALDH1A1 | |
| SCHEMBL9469466 | 0.87 | MME (0.44) | MMEALDH1A1CTSLCTSBCTSS | |
| SCHEMBL5924842 | 0.86 | MME (0.44) | MMEALDH1A1CTSLCTSBCTSS | |
| SCHEMBL9753583 | 0.86 | MME (0.44) | MMEALDH1A1CTSLCTSBCTSS | |
| SCHEMBL6804184 | 0.86 | MME (0.46) | MMEALDH1A1 | |
| SCHEMBL6804195 | 0.86 | MME (0.46) | MMEALDH1A1 | |
| SCHEMBL6806362 | 0.85 | MME (0.46) | MMEALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991010644-A1 | CYCLOALKYL-SUBSTITUTED GLUTARAMIDE DIURETIC AGENTS | PFIZER LIMITED (GB) | 1991-07-25 | — | — | WO | disclosed |