Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 13/20 | 0.63 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | CTSB | P07858 | 1/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9753887 | 1.00 | MME (0.63) | MMECTSLCTSBCTSS | |
| SCHEMBL9753884 | 1.00 | MME (0.63) | MMECTSLCTSBCTSS | |
| SCHEMBL7441985 | 0.92 | MME (0.52) | MMECTSLCTSBCTSS | |
| SCHEMBL5925045 | 0.89 | MME (0.79) | MME | |
| SCHEMBL5925066 | 0.89 | MME (0.79) | MME | |
| SCHEMBL5924893 | 0.89 | MME (0.79) | MME | |
| SCHEMBL7450171 | 0.80 | MME (0.67) | MME | |
| SCHEMBL9753583 | 0.80 | MME (0.44) | MMECTSLCTSBCTSS | |
| SCHEMBL5924842 | 0.80 | MME (0.44) | MMECTSLCTSBCTSS | |
| SCHEMBL9753945 | 0.79 | MME (0.51) | MME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991010644-A1 | CYCLOALKYL-SUBSTITUTED GLUTARAMIDE DIURETIC AGENTS | PFIZER LIMITED (GB) | 1991-07-25 | — | — | WO | disclosed |