Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ADH1B | P00325 | 1/20 | 0.31 |
| ▸ | ADH1C | P00326 | 1/20 | 0.31 |
| ▸ | ADH1A | P07327 | 1/20 | 0.31 |
| ▸ | ADH4 | P08319 | 1/20 | 0.31 |
| ▸ | ADH7 | P40394 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5684343 | 1.00 | ACE2 (0.39) | ACE2LMNAADH1BADH1CADH1A | |
| SCHEMBL9120914 | 1.00 | ACE2 (0.39) | ACE2LMNAADH1BADH1CADH1A | |
| SCHEMBL50952 | 1.00 | ACE2 (0.39) | ACE2LMNAADH1BADH1CADH1A | |
| SCHEMBL17219696 | 1.00 | ACE2 (0.39) | ACE2LMNAADH1BADH1CADH1A | |
| SCHEMBL17219108 | 1.00 | ACE2 (0.39) | ACE2LMNAADH1BADH1CADH1A | |
| SCHEMBL497377 | 0.97 | — | — | |
| SCHEMBL497386 | 0.89 | — | — | |
| SCHEMBL4452016 | 0.86 | LMNA (0.47) | ACE2LMNAADH1BADH1CADH1A | |
| SCHEMBL31730270 | 0.86 | LMNA (0.47) | ACE2LMNAADH1BADH1CADH1A | |
| SCHEMBL11216030 | 0.86 | LMNA (0.47) | ACE2LMNAADH1BADH1CADH1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991018905-A1 | RADICICOL DERIVATIVES, THEIR PREPARATION AND THEIR ANTI-TUMOR ACTIVITY | SANKYO COMPANY LIMITED (JP) | 1991-12-12 | — | — | WO | disclosed |