Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.36 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.36 |
| ▸ | ASIC3 | Q9UHC3 | 4/20 | 0.35 |
| ▸ | GRM5 | P41594 | 4/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1155254 | 0.81 | APP (0.44) | APPMAPTASIC3GRM5L3MBTL1 | |
| SCHEMBL16797165 | 0.81 | APP (0.38) | APPMAPTAKR1C2AKR1C1ASIC3 | |
| SCHEMBL29368257 | 0.80 | APP (0.36) | APPMAPTAKR1C2AKR1C1ASIC3 | |
| SCHEMBL8829831 | 0.79 | APP (0.46) | APPMAPTASIC3GRM5L3MBTL1 | |
| SCHEMBL9779861 | 0.78 | APP (0.41) | APPMAPTAKR1C2AKR1C1ASIC3 | |
| SCHEMBL5683034 | 0.78 | APP (0.55) | APPMAPTASIC3GRM5L3MBTL1 | |
| SCHEMBL536890 | 0.78 | APP (0.38) | APPMAPTAKR1C2AKR1C1ASIC3 | |
| Diphenylacetylene SCHEMBL14354086 | 0.75 | APP (0.71) | APPMAPTASIC3GRM5KDM4E | |
| SCHEMBL30015220 | 0.75 | APP (0.41) | APPMAPTASIC3GRM5KDM4E | |
| SCHEMBL426218 | 0.75 | APP (0.41) | APPMAPTASIC3GRM5KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991016344-A1 | LIGAND-LABEL CONJUGATES WHICH CONTAIN POLYOXOANIONS OF SULFUR OR PHOSPHORUS | GEORGETOWN UNIVERSITY (US) | 1991-10-31 | — | — | WO | disclosed |