Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.35 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 3/20 | 0.34 |
| ▸ | CA1 | P00915 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1180315 | 0.67 | KDM4E (0.38) | MAPTLMNAMEN1KMT2AKDM4E | |
| SCHEMBL21950893 | 0.66 | CA12 (0.48) | MAPTLMNAMEN1KMT2AKDM4E | |
| SCHEMBL13234140 | 0.65 | KDM4E (0.55) | MAPTLMNAMEN1KMT2AKDM4E | |
| SCHEMBL21950868 | 0.64 | MAPT (0.44) | MAPTLMNAMEN1KMT2AKDM4E | |
| SCHEMBL25208706 | 0.62 | MAPK1 (0.38) | MAPTLMNAMEN1KMT2AKDM4E | |
| SCHEMBL13996174 | 0.61 | MAPT (0.41) | MAPTLMNAMEN1KMT2AKDM4E | |
| SCHEMBL754466 | 0.61 | MAPT (0.39) | MAPTLMNAMEN1KMT2AKDM4E | |
| SCHEMBL10230076 | 0.60 | KDM4E (0.49) | MAPTLMNAMEN1KMT2AKDM4E | |
| SCHEMBL21338118 | 0.59 | ALDH1A1 (0.49) | MAPTLMNAMEN1KMT2AKDM4E | |
| SCHEMBL21950904 | 0.58 | KDM4E (0.46) | MAPTLMNAMEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-3181464-A | — | — | None | — | — | JP | disclosed |
| JP-H03181464-A | NICOTINIC ACID DERIVATIVE HAVING SUBSTITUTED GROUP AND PRODUCTION THEREOF | NIPPON SODA CO LTD | 1991-08-07 | — | — | JP | disclosed |