Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 2/20 | 0.35 |
| ▸ | BCHE | P06276 | 2/20 | 0.34 |
| ▸ | ACHE | P22303 | 2/20 | 0.34 |
| ▸ | CDC7 | O00311 | 1/20 | 0.34 |
| ▸ | HRH4 | Q9H3N8 | 4/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.33 |
| ▸ | CCKBR | P32239 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9632441 | 0.76 | TSHR (0.52) | TSHRTAAR1JAK2LMNABCHE | |
| SCHEMBL21895152 | 0.70 | TSHR (0.42) | TSHRJAK2 | |
| SCHEMBL9631598 | 0.70 | HRH3 (0.33) | ACHEHRH3 | |
| SCHEMBL9632921 | 0.70 | EPHX2 (0.33) | ACHE | |
| SCHEMBL9634121 | 0.69 | TSHR (0.47) | TSHRTAAR1LMNABCHEACHE | |
| SCHEMBL9754077 | 0.66 | HTR2A (0.53) | TSHR | |
| SCHEMBL9632915 | 0.66 | HTR2A (0.41) | TSHRTAAR1LMNACCKBR | |
| SCHEMBL24572017 | 0.65 | TSHR (0.61) | TSHRTAAR1LMNABCHEACHE | |
| SCHEMBL9679098 | 0.65 | TSHR (0.61) | TSHRTAAR1LMNABCHEACHE | |
| SCHEMBL24215035 | 0.65 | TSHR (0.61) | TSHRTAAR1LMNABCHEACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991008190-A1 | AMINO ACID PROTECTING GROUPS | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1991-06-13 | — | — | WO | claimed |