Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | JAK2 | O60674 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 2/20 | 0.41 |
| ▸ | ACHE | P22303 | 2/20 | 0.41 |
| ▸ | FABP7 | O15540 | 1/20 | 0.41 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2730698 | 0.83 | CA1 (0.57) | CA1CA2HTR2AKMT2AACHE | |
| SCHEMBL9754077 | 0.80 | HTR2A (0.53) | TSHRHTR2A | |
| SCHEMBL9634121 | 0.80 | TSHR (0.47) | TSHRKMT2ABCHEACHETAAR1 | |
| SCHEMBL21895152 | 0.78 | TSHR (0.42) | TSHRCA1CA2HTR2AJAK2 | |
| SCHEMBL4906918 | 0.76 | KMT2A (0.52) | CA1CA2KMT2AFABP7FABP5 | |
| SCHEMBL28310443 | 0.76 | CA1 (0.44) | TSHRCA1CA2HTR2AKMT2A | |
| SCHEMBL9754310 | 0.76 | TSHR (0.39) | TSHRJAK2BCHEACHETAAR1 | |
| SCHEMBL1275884 | 0.76 | CA1 (0.50) | CA1CA2HTR2AKMT2ABCHE | |
| SCHEMBL15436860 | 0.76 | CA1 (0.50) | CA1CA2HTR2AKMT2AFABP7 | |
| SCHEMBL1703198 | 0.73 | CA1 (0.47) | CA1CA2HTR2AKMT2ABCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5101059-A | Xanthene compounds | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1992-03-31 | — | — | US | disclosed |
| WO-1991008190-A1 | AMINO ACID PROTECTING GROUPS | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1991-06-13 | — | — | WO | disclosed |