Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | APP | P05067 | 6/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.39 |
| ▸ | CHKA | P35790 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9622502 | 1.00 | ALDH1A1 (0.48) | ALDH1A1TSHRALOX15HSD17B10MAPT | |
| SCHEMBL59844 | 0.83 | ALDH1A1 (0.69) | ALDH1A1TSHRALOX15HSD17B10MAPT | |
| Hydrochloric Acid SCHEMBL2860876 | 0.81 | ALDH1A1 (0.65) | ALDH1A1TSHRALOX15HSD17B10MAPT | |
| SCHEMBL2480761 | 0.81 | ALDH1A1 (0.65) | ALDH1A1TSHRALOX15HSD17B10MAPT | |
| SCHEMBL19994714 | 0.77 | ALDH1A1 (0.58) | ALDH1A1TSHRALOX15HSD17B10MAPT | |
| SCHEMBL29098271 | 0.75 | ALDH1A1 (0.55) | ALDH1A1TSHRALOX15HSD17B10MAPT | |
| SCHEMBL388105 | 0.75 | ALDH1A1 (0.48) | ALDH1A1TSHRMAPTTDP1MAPK1 | |
| SCHEMBL12014944 | 0.75 | ALDH1A1 (0.48) | ALDH1A1TSHRMAPTTDP1MAPK1 | |
| SCHEMBL727378 | 0.74 | ALDH1A1 (0.61) | ALDH1A1TSHRALOX15HSD17B10MAPT | |
| SCHEMBL9754288 | 0.74 | CYP2A6 (0.73) | ALDH1A1TSHRALOX15HSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991016329-A1 | ORGANOSILICIFIED COMPOUNDS AND MATERIALS AND DEVICES CONTAINING SAME | RHONE-POULENC CHIMIE (FR) | 1991-10-31 | — | — | WO | disclosed |