Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 6/20 | 0.58 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.51 |
| ▸ | MMP2 | P08253 | 1/20 | 0.51 |
| ▸ | PRMT1 | Q99873 | 2/20 | 0.48 |
| ▸ | SGMS1 | Q86VZ5 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9754248 | 0.93 | TBXA2R (0.57) | TBXA2RPRMT1SGMS1ALDH1A1TP53 | |
| SCHEMBL9754254 | 0.88 | TBXA2R (0.56) | TBXA2RPRMT1SGMS1ALDH1A1TP53 | |
| SCHEMBL9754221 | 0.87 | TBXA2R (0.47) | TBXA2RPRMT1SGMS1AKR1C3TBXAS1 | |
| SCHEMBL9754213 | 0.84 | TBXA2R (0.69) | TBXA2RPRMT1ALDH1A1TP53GAA | |
| SCHEMBL9754561 | 0.83 | TBXA2R (0.60) | TBXA2RADAMTS5MMP2PRMT1SGMS1 | |
| SCHEMBL9754558 | 0.83 | TBXA2R (0.60) | TBXA2RADAMTS5MMP2PRMT1SGMS1 | |
| SCHEMBL9754328 | 0.83 | TBXA2R (0.62) | TBXA2RPRMT1SGMS1ALDH1A1TP53 | |
| SCHEMBL9850570 | 0.81 | SGMS1 (0.60) | TBXA2RADAMTS5MMP2SGMS1 | |
| SCHEMBL9754313 | 0.81 | TBXA2R (0.57) | TBXA2RADAMTS5MMP2PRMT1SGMS1 | |
| SCHEMBL9754308 | 0.81 | TBXA2R (0.57) | TBXA2RADAMTS5MMP2PRMT1SGMS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991013868-A1 | PHENYLTHIOALKYLCARBOXYLIC ACID DERIVATIVES, METHOD FOR PREPARING THEM AND DRUGS CONTAINING THESE COMPOUNDS | BOEHRINGER MANNHEIM GMBH (DE) | 1991-09-19 | — | — | WO | disclosed |