Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 7/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | SGMS1 | Q86VZ5 | 2/20 | 0.48 |
| ▸ | PRMT1 | Q99873 | 2/20 | 0.48 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.48 |
| ▸ | TBXAS1 | P24557 | 3/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9754213 | 0.90 | TBXA2R (0.69) | TBXA2RALDH1A1PRMT1AKR1C3TBXAS1 | |
| SCHEMBL9754248 | 0.84 | TBXA2R (0.57) | TBXA2RALDH1A1SGMS1PRMT1AKR1C3 | |
| SCHEMBL9754254 | 0.83 | TBXA2R (0.56) | TBXA2RALDH1A1SGMS1PRMT1AKR1C3 | |
| SCHEMBL9754344 | 0.83 | TBXA2R (0.58) | TBXA2RALDH1A1SGMS1PRMT1AKR1C3 | |
| SCHEMBL9754342 | 0.82 | TBXA2R (0.64) | TBXA2RALDH1A1SGMS1PRMT1AKR1C3 | |
| SCHEMBL9850482 | 0.80 | SGMS1 (0.66) | TBXA2RSGMS1TBXAS1 | |
| SCHEMBL9754244 | 0.79 | TBXA2R (0.61) | TBXA2RALDH1A1SGMS1PRMT1AKR1C3 | |
| SCHEMBL14327858 | 0.77 | TBXA2R (1.00) | TBXA2RALDH1A1TBXAS1 | |
| SCHEMBL15078819 | 0.77 | TBXA2R (0.81) | TBXA2RALDH1A1PRMT1AKR1C3TBXAS1 | |
| SCHEMBL9131036 | 0.76 | TBXA2R (0.82) | TBXA2RALDH1A1PRMT1AKR1C3TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991013868-A1 | PHENYLTHIOALKYLCARBOXYLIC ACID DERIVATIVES, METHOD FOR PREPARING THEM AND DRUGS CONTAINING THESE COMPOUNDS | BOEHRINGER MANNHEIM GMBH (DE) | 1991-09-19 | — | — | WO | disclosed |