Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 5/20 | 0.58 |
| ▸ | SRC | P12931 | 1/20 | 0.46 |
| ▸ | TRPM4 | Q8TD43 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28295682 | 0.82 | GPR84 (0.67) | GPR84SRCTRPM4ALDH1A1L3MBTL1 | |
| SCHEMBL27538515 | 0.81 | GPR84 (0.51) | GPR84SRCALDH1A1POLBTDP1 | |
| SCHEMBL10792972 | 0.78 | GPR84 (0.58) | GPR84SRCALDH1A1POLBTDP1 | |
| Ethylene SCHEMBL28651302 | 0.77 | SRC (0.67) | GPR84SRCALDH1A1POLBTDP1 | |
| SCHEMBL27676341 | 0.77 | SRC (0.73) | GPR84SRCALDH1A1POLBTDP1 | |
| SCHEMBL37038 | 0.77 | SRC (0.73) | GPR84SRCALDH1A1POLBTDP1 | |
| Benzene SCHEMBL11142811 | 0.77 | SRC (0.73) | GPR84SRCALDH1A1POLBTDP1 | |
| SCHEMBL20676950 | 0.76 | SRC (0.50) | GPR84SRCALDH1A1POLBTDP1 | |
| SCHEMBL30469411 | 0.76 | SRC (0.50) | GPR84SRCALDH1A1POLBTDP1 | |
| SCHEMBL2474829 | 0.76 | HPRT1 (0.48) | GPR84ALDH1A1TDP1L3MBTL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991017987-A1 | PHENOL AND PYRIDINOL DERIVATIVES AS PHARMACEUTICALS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1991-11-28 | — | — | WO | disclosed |