Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | DHODH | Q02127 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | GCGR | P47871 | 1/20 | 0.45 |
| ▸ | MMP2 | P08253 | 2/20 | 0.44 |
| ▸ | MMP1 | P03956 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9130046 | 0.90 | TDP1 (0.58) | TDP1ALDH1A1L3MBTL1LMNAPRKCZ | |
| SCHEMBL9754386 | 0.84 | TDP1 (0.51) | TDP1ALDH1A1NPSR1L3MBTL1LMNA | |
| SCHEMBL3919215 | 0.83 | TDP1 (0.71) | TDP1ALDH1A1L3MBTL1LMNAKMT2A | |
| SCHEMBL9754631 | 0.82 | CA12 (0.66) | ALOX5ALDH1A1NPSR1LMNAPRKCZ | |
| SCHEMBL6832244 | 0.80 | TDP1 (0.59) | TDP1ALOX5ALDH1A1L3MBTL1LMNA | |
| SCHEMBL9754382 | 0.77 | CA1 (0.55) | ALDH1A1CYP3A4CYP2C9CYP2C19DHODH | |
| SCHEMBL9754628 | 0.77 | DHODH (0.43) | ALDH1A1CYP1A2CYP2C9CYP2C19NPSR1 | |
| SCHEMBL23703782 | 0.76 | TDP1 (0.76) | TDP1ALDH1A1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL31636931 | 0.75 | TDP1 (0.50) | TDP1ALDH1A1L3MBTL1LMNAPRKCZ | |
| SCHEMBL25811868 | 0.75 | GCGR (0.48) | TDP1ALOX5ALDH1A1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991013065-A1 | 6-ARYL-2-SUBSTITUTED BENZOIC ACID HERBICIDES | FMC CORPORATION (US) | 1991-09-05 | — | — | WO | disclosed |