SCHEMBL9754382

SCHEMBL9754382

O=C(O)c1c(O)cccc1-c1ccc(Cl)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 3/20 0.55
CA2 P00918 3/20 0.55
CA12 O43570 2/20 0.55
CA9 Q16790 2/20 0.55
CA7 P43166 1/20 0.55
CA14 Q9ULX7 1/20 0.55
DHODH Q02127 2/20 0.51
CYP3A4 P08684 1/20 0.51
CYP2C8 P10632 1/20 0.51
CYP2C9 P11712 1/20 0.51
ALDH1A1 P00352 2/20 0.48
NPC1 O15118 2/20 0.48
MAPT P10636 2/20 0.48
RAB9A P51151 2/20 0.48
SMN1; SMN2 Q16637 2/20 0.48
KDM4E B2RXH2 1/20 0.48
ANO1 Q5XXA6 3/20 0.46
SLC6A4 P31645 1/20 0.42
SLC6A3 Q01959 1/20 0.42
PTGS1 P23219 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3264678 0.85 CA12 (0.64) CA1CA2CA12CA9CA7
SCHEMBL23354090 0.84 ANO1 (0.57) DHODHCYP3A4CYP2C8CYP2C9ALDH1A1
SCHEMBL10046425 0.82 CA12 (0.80) CA1CA2CA12CA9CA7
SCHEMBL29979189 0.81 DHODH (0.47) DHODHCYP3A4CYP2C8CYP2C9ALDH1A1
SCHEMBL23354124 0.81 DHODH (0.47) DHODHCYP3A4CYP2C8CYP2C9ALDH1A1
SCHEMBL31067160 0.78 CA12 (0.59) CA1CA2CA12CA9CA7
SCHEMBL25285914 0.77 CA12 (0.61) CA1CA2CA12CA9CA7
SCHEMBL9754422 0.77 CA1 (0.48) CA1CA2CA12CA9CA7
SCHEMBL9754631 0.77 CA12 (0.66) CA1CA2CA12CA9CA7
SCHEMBL9754469 0.77 TDP1 (0.51) DHODHCYP3A4CYP2C9ALDH1A1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1991013065-A1 6-ARYL-2-SUBSTITUTED BENZOIC ACID HERBICIDES FMC CORPORATION (US) 1991-09-05 WO disclosed