Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7138050 | 0.82 | KMT2A (0.51) | KMT2AALDH1A1MEN1KDM4ENLRP3 | |
| SCHEMBL16332165 | 0.82 | KMT2A (0.51) | KMT2AALDH1A1MEN1KDM4ENLRP3 | |
| SCHEMBL7464196 | 0.82 | KMT2A (0.54) | KMT2AALDH1A1MEN1KDM4ENLRP3 | |
| SCHEMBL14172844 | 0.80 | SMN1; SMN2 (0.56) | KMT2AALDH1A1MEN1SMN1; SMN2NLRP3 | |
| SCHEMBL14266385 | 0.80 | KMT2A (0.53) | KMT2AALDH1A1MEN1NLRP3LMNA | |
| SCHEMBL9754154 | 0.80 | FUCA1 (0.47) | KMT2AALDH1A1MEN1SMN1; SMN2CYP3A4 | |
| SCHEMBL5805448 | 0.80 | KMT2A (0.53) | KMT2AALDH1A1MEN1NLRP3THRB | |
| SCHEMBL5805446 | 0.80 | KMT2A (0.53) | KMT2AALDH1A1MEN1KDM4ENLRP3 | |
| SCHEMBL15145816 | 0.80 | KMT2A (0.53) | KMT2AALDH1A1MEN1NLRP3THRB | |
| SCHEMBL1428912 | 0.80 | KMT2A (0.53) | KMT2AALDH1A1MEN1KDM4ENLRP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991015464-A1 | AMIDE ESTER ACAT INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1991-10-17 | — | — | WO | claimed |