Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FUCA1 | P04066 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | GPR17 | Q13304 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9754491 | 0.80 | KMT2A (0.55) | SMN1; SMN2KMT2AMEN1ALDH1A1CYP3A4 | |
| SCHEMBL3954552 | 0.80 | ALDH1A1 (0.49) | FUCA1SMN1; SMN2RAB9AALDH1A1GAA | |
| SCHEMBL6273637 | 0.80 | FUCA1 (0.47) | FUCA1SMN1; SMN2KMT2ACES2CES1 | |
| SCHEMBL2092769 | 0.79 | RAPGEF4 (0.42) | FUCA1SMN1; SMN2KMT2AMEN1RAB9A | |
| SCHEMBL15480436 | 0.78 | HDAC3 (0.49) | FUCA1SMN1; SMN2POLBKMT2AMEN1 | |
| SCHEMBL2710816 | 0.78 | KMT2A (0.53) | POLBKMT2AMEN1ALDH1A1GAA | |
| SCHEMBL18190919 | 0.78 | GRIN2D (0.42) | FUCA1SMN1; SMN2GPR17KMT2AMEN1 | |
| SCHEMBL18415476 | 0.76 | CES2 (0.43) | FUCA1SMN1; SMN2KMT2ARAB9ACES2 | |
| SCHEMBL8234531 | 0.76 | RAB9A (0.63) | FUCA1SMN1; SMN2POLBKMT2AMEN1 | |
| SCHEMBL13973099 | 0.74 | FUCA1 (0.43) | FUCA1SMN1; SMN2KMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991015464-A1 | AMIDE ESTER ACAT INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1991-10-17 | — | — | WO | claimed |