Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 6/20 | 0.58 |
| ▸ | CSNK2A1 | P68400 | 5/20 | 0.58 |
| ▸ | CSNK2A2 | P19784 | 4/20 | 0.58 |
| ▸ | CSNK2B | P67870 | 4/20 | 0.58 |
| ▸ | CSNK2A3 | Q8NEV1 | 4/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 3/20 | 0.43 |
| ▸ | CA12 | O43570 | 2/20 | 0.43 |
| ▸ | CA3 | P07451 | 2/20 | 0.43 |
| ▸ | CA4 | P22748 | 2/20 | 0.43 |
| ▸ | CA6 | P23280 | 2/20 | 0.43 |
| ▸ | CA7 | P43166 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9754470 | 0.92 | PIM1 (0.63) | PIM1CSNK2A1CSNK2A2CSNK2BCSNK2A3 | |
| SCHEMBL9754548 | 0.81 | AKR1B1 (0.52) | KDM4EGLAMAPTHPGDTSHR | |
| SCHEMBL9754537 | 0.78 | PIM1 (0.62) | PIM1CSNK2A1CSNK2A2CSNK2BCSNK2A3 | |
| SCHEMBL9754521 | 0.75 | CA12 (0.39) | KDM4EMAPTHPGDTSHRHTT | |
| SCHEMBL11861457 | 0.74 | TTR (0.65) | KDM4EHPGDHSD17B10CA2CA12 | |
| SCHEMBL9754462 | 0.73 | MAOB (0.54) | KDM4EGLAHPGDHTTCA2 | |
| SCHEMBL9754557 | 0.72 | CA12 (0.39) | PIM1CSNK2A1CSNK2A2CSNK2BCSNK2A3 | |
| SCHEMBL2958769 | 0.71 | AHR (0.53) | KDM4EMAPTHPGDTSHRALDH1A1 | |
| SCHEMBL10867585 | 0.69 | MAOA (0.63) | KDM4EGLAMAPTHPGDHSD17B10 | |
| SCHEMBL14304000 | 0.67 | CA12 (0.44) | TDP1L3MBTL1CA2CA12CA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991014688-A1 | HETERO POLYCYCLIC BIOCIDAL COMPOUNDS AND THEIR USE IN MEDECINE | THE WELLCOME FOUNDATION LIMITED (GB) | 1991-10-03 | — | — | WO | disclosed |
| EP-0447703-A1 | Hetero polycyclic biocidal compounds, their synthesis and intermediates therefor,formulations containing them and their use in medicine | THE WELLCOME FOUNDATION LIMITED (GB) | 1991-09-25 | — | — | EP | disclosed |