Acifluorfen

Acifluorfen

SCHEMBL9754523

CCc1cccc(C)c1CC(N)=O.CCc1cccc(CC)c1N(COC)C(=O)CCl.CCc1cccc(CC)c1N(COC)C(=O)CCl.O=C(O)c1cc(Oc2ccc(C(F)(F)F)cc2Cl)ccc1[N+](=O)[O-].O=C(O)c1cc(Oc2ccc(C(F)(F)F)cc2Cl)ccc1[N+](=O)[O-]

nearest known ligand 0.54

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 4/20 0.54
MEN1 O00255 3/20 0.54
KMT2A Q03164 3/20 0.54
TTR P02766 1/20 0.54
PPOX P50336 1/20 0.54
MRGPRX4 Q96LA9 5/20 0.40
TP53 P04637 2/20 0.40
LMNA P02545 4/20 0.35
SMN1; SMN2 Q16637 3/20 0.35
ALDH1A1 P00352 2/20 0.35
POLB P06746 2/20 0.35
PYGL P06737 1/20 0.35
CYP3A4 P08684 1/20 0.34
MAPT P10636 2/20 0.34
FFAR1 O14842 2/20 0.33
CCR6 P51684 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
GPR55 Q9Y2T6 1/20 0.32
PPARG P37231 1/20 0.32
PPARD Q03181 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acifluorfen SCHEMBL7586706 0.92 TDP1 (0.65) TDP1MEN1KMT2ATTRPPOX
Acifluorfen SCHEMBL9691694 0.86 TDP1 (0.61) TDP1MEN1KMT2ATTRPPOX
Acifluorfen SCHEMBL7575506 0.86 TDP1 (0.61) TDP1MEN1KMT2ATTRPPOX
Acifluorfen SCHEMBL9752491 0.85 TDP1 (0.61) TDP1MEN1KMT2ATTRPPOX
Acifluorfen SCHEMBL7579654 0.83 TDP1 (0.54) TDP1MEN1KMT2ATTRPPOX
Alachlor SCHEMBL7578823 0.83 TDP1 (0.51) TDP1MEN1KMT2ATTRPPOX
Acifluorfen SCHEMBL7584244 0.83 TDP1 (0.52) TDP1MEN1KMT2ATTRPPOX
Acifluorfen SCHEMBL7576539 0.83 TDP1 (0.53) TDP1MEN1KMT2ATTRPPOX
Oxyfluorfen SCHEMBL7589730 0.83 MEN1 (0.50) TDP1MEN1KMT2ATTRPPOX
Acifluorfen SCHEMBL9451020 0.82 TDP1 (0.56) TDP1MEN1KMT2ATTRPPOX

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1991015478-A1 CROP-SELECTIVE HERBICIDAL SULFONAMIDES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1991-10-17 WO disclosed