Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | TTR | P02766 | 1/20 | 0.61 |
| ▸ | PPOX | P50336 | 1/20 | 0.61 |
| ▸ | MRGPRX4 | Q96LA9 | 6/20 | 0.44 |
| ▸ | PYGL | P06737 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.35 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.35 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.35 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acifluorfen SCHEMBL9754523 | 0.85 | TDP1 (0.54) | TDP1MEN1KMT2ATTRPPOX | |
| Acifluorfen SCHEMBL9698657 | 0.84 | TDP1 (0.86) | TDP1MEN1KMT2ATTRPPOX | |
| Acifluorfen SCHEMBL9675679 | 0.82 | TDP1 (0.56) | TDP1MEN1KMT2ATTRPPOX | |
| Acifluorfen SCHEMBL9451020 | 0.82 | TDP1 (0.56) | TDP1MEN1KMT2ATTRPPOX | |
| Acifluorfen SCHEMBL9715148 | 0.79 | TDP1 (0.71) | TDP1MEN1KMT2ATTRPPOX | |
| Acifluorfen SCHEMBL9539519 | 0.79 | TDP1 (0.49) | TDP1MEN1KMT2ATTRPPOX | |
| Acifluorfen SCHEMBL29445767 | 0.78 | TDP1 (1.00) | TDP1MEN1KMT2ATTRPPOX | |
| Acifluorfen SCHEMBL29448829 | 0.78 | TDP1 (1.00) | TDP1MEN1KMT2ATTRPPOX | |
| Acifluorfen SCHEMBL8028079 | 0.78 | TDP1 (1.00) | TDP1MEN1KMT2ATTRPPOX | |
| Acifluorfen SCHEMBL3228873 | 0.78 | TDP1 (1.00) | TDP1MEN1KMT2ATTRPPOX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991010653-A1 | HERBICIDAL PYRIMIDINES AND TRIAZINES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-07-25 | — | — | WO | disclosed |
| WO-1991010668-A1 | HERBICIDAL SULFONYLUREAS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-07-25 | — | — | WO | disclosed |