SCHEMBL9754534

SCHEMBL9754534

Cn1c2ccccc2c2ccc3sc(CNC(C)(CO)CO)cc3c21

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALKBH5 Q6P6C2 1/20 0.35
FTO Q9C0B1 1/20 0.35
HSP90AA1 P07900 1/20 0.35
IDO1 P14902 1/20 0.35
KDM4E B2RXH2 9/20 0.33
HPGD P15428 7/20 0.33
HSD17B10 Q99714 5/20 0.33
MAPT P10636 2/20 0.33
NPSR1 Q6W5P4 2/20 0.33
TSHR P16473 1/20 0.33
SLC2A1 P11166 1/20 0.33
ALDH1A1 P00352 6/20 0.33
LMNA P02545 1/20 0.33
KMT2A Q03164 1/20 0.33
GFER P55789 1/20 0.33
KIF11 P52732 1/20 0.33
GPR3 P46089 1/20 0.33
ABL1 P00519 1/20 0.32
CYP1A2 P05177 1/20 0.32
CYP3A4 P08684 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9843508 0.95 SLC2A1 (0.41) ALKBH5FTOHSP90AA1IDO1KDM4E
SCHEMBL9843510 0.88 SLC2A1 (0.34) HSP90AA1IDO1KDM4EHPGDHSD17B10
SCHEMBL9779073 0.79 SLC2A1 (0.43) ALKBH5FTOHSP90AA1IDO1KDM4E
Hydrochloric Acid SCHEMBL9779120 0.78 SLC2A1 (0.43) ALKBH5FTOHSP90AA1IDO1KDM4E
SCHEMBL9525894 0.77 SLC2A1 (0.42) SLC2A1KMT2A
Hydrochloric Acid SCHEMBL9526275 0.76 SLC2A1 (0.41) SLC2A1KMT2A
SCHEMBL9754530 0.72 SLC2A1 (0.48) ALKBH5FTOKDM4EHPGDHSD17B10
SCHEMBL9754468 0.72 SLC2A1 (0.37) MAPTNPSR1SLC2A1ALDH1A1RXFP1
Hydrochloric Acid SCHEMBL9754640 0.72 SLC2A1 (0.36) MAPTNPSR1SLC2A1ALDH1A1RXFP1
SCHEMBL9754616 0.70 SLC2A1 (0.39) ALKBH5FTOKDM4EHPGDHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1991014688-A1 HETERO POLYCYCLIC BIOCIDAL COMPOUNDS AND THEIR USE IN MEDECINE THE WELLCOME FOUNDATION LIMITED (GB) 1991-10-03 WO disclosed
EP-0447703-A1 Hetero polycyclic biocidal compounds, their synthesis and intermediates therefor,formulations containing them and their use in medicine THE WELLCOME FOUNDATION LIMITED (GB) 1991-09-25 EP disclosed