Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 5/20 | 0.34 |
| ▸ | MAPT | P10636 | 6/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 3/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.32 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.31 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9754640 | 0.99 | SLC2A1 (0.36) | SLC2A1TP53MAPTRXFP1ALDH1A1 | |
| SCHEMBL9529107 | 0.79 | PTPN7 (0.45) | SLC2A1MAPTALDH1A1PDCD1CD274 | |
| Hydrochloric Acid SCHEMBL9526374 | 0.78 | PTPN7 (0.44) | SLC2A1MAPTALDH1A1PDCD1CD274 | |
| SCHEMBL9539120 | 0.74 | SLC2A1 (0.39) | SLC2A1MAPTALDH1A1NPSR1TRPV1 | |
| SCHEMBL9754616 | 0.74 | SLC2A1 (0.39) | SLC2A1MAPTRXFP1ALDH1A1CD274 | |
| Hydrochloric Acid SCHEMBL9779007 | 0.73 | SLC2A1 (0.38) | SLC2A1MAPTALDH1A1NPSR1TRPV1 | |
| Hydrochloric Acid SCHEMBL9754584 | 0.73 | SLC2A1 (0.38) | SLC2A1MAPTRXFP1ALDH1A1CD274 | |
| SCHEMBL10682965 | 0.73 | SLC2A1 (0.40) | SLC2A1ALDH1A1PDCD1CD274 | |
| SCHEMBL9754534 | 0.72 | ALKBH5 (0.35) | SLC2A1MAPTRXFP1ALDH1A1NPSR1 | |
| SCHEMBL9536888 | 0.72 | SLC2A1 (0.52) | SLC2A1TP53MAPTALDH1A1CD274 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0447703-A1 | Hetero polycyclic biocidal compounds, their synthesis and intermediates therefor,formulations containing them and their use in medicine | THE WELLCOME FOUNDATION LIMITED (GB) | 1991-09-25 | — | — | EP | claimed |
| US-4999369-A | Antitumor agents | BURROUGHS WELLCOME CO. (US) | 1991-03-12 | — | — | US | claimed |
| WO-1991014688-A1 | HETERO POLYCYCLIC BIOCIDAL COMPOUNDS AND THEIR USE IN MEDECINE | THE WELLCOME FOUNDATION LIMITED (GB) | 1991-10-03 | — | — | WO | disclosed |
| EP-0447703-A1 | Hetero polycyclic biocidal compounds, their synthesis and intermediates therefor,formulations containing them and their use in medicine | THE WELLCOME FOUNDATION LIMITED (GB) | 1991-09-25 | — | — | EP | disclosed |
| US-4999369-A | Antitumor agents | BURROUGHS WELLCOME CO. (US) | 1991-03-12 | — | — | US | disclosed |
| US-4910218-A | With a hydroxy containing secondary amine group | BURROUGHS WELLCOME CO. (US) | 1990-03-20 | — | — | US | disclosed |