Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Ricinoleic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 2/20 | 0.65 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.65 |
| ▸ | FAAH | O00519 | 3/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.51 |
| ▸ | RELA | Q04206 | 1/20 | 0.51 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.46 |
| ▸ | PTGFR | P43088 | 1/20 | 0.46 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.46 |
| ▸ | PPARD | Q03181 | 4/20 | 0.46 |
| ▸ | PPARA | Q07869 | 4/20 | 0.46 |
| ▸ | PPARG | P37231 | 4/20 | 0.45 |
| ▸ | TERT | O14746 | 3/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | BLM | P54132 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | FABP4 | P15090 | 2/20 | 0.45 |
| ▸ | GMNN | O75496 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Myristic Acid SCHEMBL28129925 | 0.84 | TRPA1 (0.58) | FFAR1FFAR4TBXA2RPTGFRPTGER2 | |
| Menthol SCHEMBL27925157 | 0.84 | TRPA1 (0.58) | FFAR1FFAR4TBXA2RPTGFRPTGER2 | |
| Stearic Acid SCHEMBL27339395 | 0.84 | TRPA1 (0.58) | FFAR1FFAR4TBXA2RPTGFRPTGER2 | |
| Myristic Acid SCHEMBL28129926 | 0.84 | TRPA1 (0.58) | FFAR1FFAR4TBXA2RPTGFRPTGER2 | |
| Ricinoleic Acid SCHEMBL23532631 | 0.80 | FFAR1 (1.00) | FFAR1FFAR4FAAHNFKB1NFKB2 | |
| Ricinoleic Acid SCHEMBL25248998 | 0.80 | FFAR1 (1.00) | FFAR1FFAR4FAAHNFKB1NFKB2 | |
| SCHEMBL9721106 | 0.80 | FFAR1 (1.00) | FFAR1FFAR4FAAHNFKB1NFKB2 | |
| SCHEMBL23925391 | 0.80 | FFAR1 (1.00) | FFAR1FFAR4FAAHNFKB1NFKB2 | |
| SCHEMBL22400911 | 0.80 | FFAR1 (1.00) | FFAR1FFAR4FAAHNFKB1NFKB2 | |
| SCHEMBL21712 | 0.80 | FFAR1 (1.00) | FFAR1FFAR4FAAHNFKB1NFKB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991015269-A1 | NON-TOXIC FIRE EXTINGUISHANT | TAG INVESTMENTS INC. (CA) | 1991-10-17 | — | — | WO | disclosed |