Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.49 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | XBP1 | P17861 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2493912 | 0.98 | LIPG (0.50) | KCNH3LIPGMAPTLMNAXBP1 | |
| SCHEMBL31548023 | 0.98 | LIPG (0.50) | KCNH3LIPGMAPTLMNAXBP1 | |
| SCHEMBL11609802 | 0.98 | LIPG (0.50) | KCNH3LIPGMAPTLMNAXBP1 | |
| SCHEMBL11213224 | 0.98 | LIPG (0.50) | KCNH3LIPGMAPTLMNAXBP1 | |
| SCHEMBL2539193 | 0.95 | MAPT (0.44) | KCNH3LIPGMAPTLMNAXBP1 | |
| SCHEMBL14320957 | 0.93 | LIPG (0.51) | KCNH3LIPGMAPTLMNAXBP1 | |
| SCHEMBL11380769 | 0.93 | LIPG (0.51) | KCNH3LIPGMAPTLMNAXBP1 | |
| SCHEMBL14321012 | 0.89 | CYP3A4 (0.42) | KCNH3LIPGMAPTLMNAXBP1 | |
| SCHEMBL7982172 | 0.87 | MAPT (0.47) | KCNH3MAPTLMNAHSD17B10KDM4E | |
| SCHEMBL1567827 | 0.87 | LIPG (0.56) | LIPGBIDMCL1BCL2L1BAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-3056451-A | — | — | None | — | — | JP | disclosed |
| JP-H0356451-A | NOVEL DIPHENYLAMINE DERIVATIVE AND PRODUCTION THEREOF | MITSUI TOATSU CHEM INC | 1991-03-12 | — | — | JP | disclosed |
| US-4362893-A | Preparation of C-nitrosodiarylamines from diarylamines | UOP INC. (US) | 1982-12-07 | — | — | US | disclosed |
| US-4151198-A | Resolution of N-acyl-DL (+)-phenylalanines | AMERICAN CYANAMID COMPANY (US) | 1979-04-24 | — | — | US | disclosed |