Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 3/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 2/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | CTSG | P08311 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | PLA2G4A | P47712 | 2/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | PLA2G6 | O60733 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | ECE1 | P42892 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7859632 | 1.00 | FAAH (0.36) | FAAHCHRM1MGLLELANEF2 | |
| SCHEMBL8834472 | 0.93 | FAAH (0.35) | FAAHCHRM1MGLLELANEF2 | |
| SCHEMBL9020169 | 0.86 | CHRM1 (0.38) | FAAHCHRM1MGLLELANEF2 | |
| SCHEMBL9596161 | 0.85 | FAAH (0.36) | FAAHCHRM1MGLLELANEF2 | |
| SCHEMBL9567073 | 0.85 | FAAH (0.36) | FAAHCHRM1MGLLELANEF2 | |
| SCHEMBL9567072 | 0.85 | FAAH (0.36) | FAAHCHRM1MGLLELANEF2 | |
| SCHEMBL9596152 | 0.85 | FAAH (0.36) | FAAHCHRM1MGLLELANEF2 | |
| SCHEMBL9754678 | 0.85 | CHRM1 (0.37) | FAAHCHRM1MGLLELANEF2 | |
| SCHEMBL9215878 | 0.85 | CHRM1 (0.37) | FAAHCHRM1MGLLELANEF2 | |
| SCHEMBL8098583 | 0.85 | CHRM1 (0.37) | FAAHCHRM1MGLLELANEF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991014687-A1 | 2-(SUBSTITUTED PYRROLIDINYLTHIO)CARBAPENEM DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1991-10-03 | — | — | WO | disclosed |