Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CCR5 | P51681 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.34 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9020164 | 1.00 | ATM (0.43) | ATMALDH1A1MAPTHPGDTDP1 | |
| SCHEMBL9020318 | 0.87 | ATM (0.45) | ATMALDH1A1MAPTHPGDTDP1 | |
| SCHEMBL9020149 | 0.87 | ATM (0.44) | ATMALDH1A1MAPTHPGDTDP1 | |
| SCHEMBL9020388 | 0.83 | ATM (0.41) | ATMALDH1A1MAPTHPGDTDP1 | |
| SCHEMBL9020543 | 0.83 | ATM (0.38) | ATMALDH1A1MAPTHPGDTDP1 | |
| SCHEMBL9519199 | 0.82 | PREP (0.43) | ATMALDH1A1MAPTHPGDTDP1 | |
| SCHEMBL9020004 | 0.81 | CCR5 (0.41) | ATMALDH1A1MAPTHPGDTDP1 | |
| SCHEMBL9399680 | 0.81 | CCR5 (0.42) | ATMALDH1A1MAPTHPGDTDP1 | |
| SCHEMBL9519307 | 0.81 | PREP (0.42) | ATMALDH1A1MAPTHPGDTDP1 | |
| SCHEMBL9520655 | 0.81 | PREP (0.44) | ATMALDH1A1MAPTHPGDTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991014687-A1 | 2-(SUBSTITUTED PYRROLIDINYLTHIO)CARBAPENEM DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1991-10-03 | — | — | WO | disclosed |