SCHEMBL9754777

SCHEMBL9754777

OCCNc1nc(Cl)nc(NCCO)n1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.70
CA12 O43570 2/20 0.54
CA1 P00915 2/20 0.54
CA2 P00918 2/20 0.54
CA9 Q16790 2/20 0.54
CA14 Q9ULX7 2/20 0.54
CA5A P35218 1/20 0.54
CA5B Q9Y2D0 1/20 0.54
MAPT P10636 1/20 0.54
LMNA P02545 1/20 0.54
ABCG2 Q9UNQ0 1/20 0.54
RECQL P46063 1/20 0.50
MCL1 Q07820 1/20 0.50
MEN1 O00255 1/20 0.50
GAA P10253 1/20 0.50
MAPK1 P28482 1/20 0.50
NR1I2 O75469 1/20 0.43
AHR P35869 1/20 0.43
SLC29A1 Q99808 2/20 0.43
HPGD P15428 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9188023 0.95 KMT2A (0.65) KMT2ACA12CA1CA2CA9
SCHEMBL14065504 0.90 LMNA (0.73) KMT2ACA12CA1CA2CA9
SCHEMBL1032510 0.87 KMT2A (0.60) KMT2ARECQLMCL1MEN1GAA
SCHEMBL29391675 0.86 KMT2A (0.56) KMT2ACA12CA1CA2CA9
SCHEMBL4376048 0.86 KMT2A (0.60) KMT2ACA12CA1CA2CA9
SCHEMBL6640707 0.83 KMT2A (0.72) KMT2ACA12CA1CA2CA9
SCHEMBL11751314 0.82 KMT2A (0.65) KMT2ACA12CA1CA2CA9
SCHEMBL9357110 0.82 KMT2A (0.61) KMT2ACA12CA1CA2CA9
SCHEMBL10057870 0.81 KMT2A (0.51) KMT2ACA12CA1CA2CA9
SCHEMBL3500281 0.81 RECQL (0.84) KMT2ACA12CA1CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9434808-B2 Process for preparing polymers, polymers, dispersions, inks and uses FUJIFILM IMAGING COLORANTS LIMITED (GB) 2016-09-06 US disclosed
US-9434808-B2 Process for preparing polymers, polymers, dispersions, inks and uses FUJIFILM IMAGING COLORANTS LIMITED (GB) 2016-09-06 US disclosed
US-20140309364-A1 Process for Preparing Polymers, Polymers, Dispersions, Inks and Uses FUJIFILM IMAGING COLORANTS LIMITED (GB) 2014-10-16 US disclosed
US-20140309364-A1 Process for Preparing Polymers, Polymers, Dispersions, Inks and Uses FUJIFILM IMAGING COLORANTS LIMITED (GB) 2014-10-16 US disclosed
EP-2729542-B1 PROCESS FOR PREPARING POLYMERS, POLYMERS, DISPERSIONS, INKS AND USES FUJIFILM IMAGING COLORANTS LTD (GB) 2014-10-15 EP disclosed
US-20140168333-A1 Dispersion, Ink and Process FUJIFILM IMAGING COLORANTS LIMITED (GB) 2014-06-19 US disclosed
US-20140168333-A1 Dispersion, Ink and Process FUJIFILM IMAGING COLORANTS LIMITED (GB) 2014-06-19 US disclosed
WO-2013005019-A2 PROCESS FOR PREPARING POLYMERS, POLYMERS, DISPERSIONS, INKS AND USES FUJIFILM IMAGING COLORANTS LIMITED (GB) 2013-01-10 WO disclosed
WO-1991013881-A1 PARAPHENYLENEDIAMINE DERIVATIVES AND THEIR USE IN OXIDATIVE DYES HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1991-09-19 WO disclosed
EP-0255801-B1 ANILINOTRIAZINES AND THEIR USE CIBA-GEIGY AG (CH) 1990-11-28 EP disclosed
US-4786672-A STABILIZATION OF POLYVINYL CHLORIDE CIBA-GEIGY CORPORATION (US) 1988-11-22 US disclosed
EP-0255801-A2 Anilinotriazines and their use CIBA-GEIGY AG (CH) 1988-02-10 EP disclosed