Phosphine

Phosphine

SCHEMBL9754815

COc1ccc(Br)cc1.P

nearest known ligand 0.65

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.65
CA2 P00918 2/20 0.65
CA7 P43166 2/20 0.65
CA9 Q16790 2/20 0.65
CA12 O43570 1/20 0.65
CA14 Q9ULX7 1/20 0.65
RAB9A P51151 4/20 0.64
MAPT P10636 3/20 0.64
MAPK1 P28482 3/20 0.64
MEN1 O00255 2/20 0.64
KMT2A Q03164 2/20 0.64
LMNA P02545 2/20 0.64
NPSR1 Q6W5P4 2/20 0.64
RXFP1 Q9HBX9 1/20 0.64
MAOA P21397 2/20 0.57
MAOB P27338 2/20 0.57
NPC1 O15118 3/20 0.55
GAA P10253 2/20 0.55
L3MBTL1 Q9Y468 2/20 0.55
ACHE P22303 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9301 0.97
Bromomethane SCHEMBL9702151 0.94 CA1 (0.65) CA1CA2CA7CA9CA12
SCHEMBL5466009 0.94 CA1 (0.65) CA1CA2CA7CA9CA12
Magnesium SCHEMBL31191739 0.94 CA1 (0.65) CA1CA2CA7CA9CA12
SCHEMBL109479 0.94 CA1 (0.65) CA1CA2CA7CA9CA12
SCHEMBL10605468 0.94 CA1 (0.65) CA1CA2CA7CA9CA12
Methyl Alcohol SCHEMBL27852458 0.92 MEN1 (0.68) CA1CA2CA7CA9CA12
Ethylene SCHEMBL27510996 0.92 RAB9A (0.61) CA1CA2CA7CA9CA12
Bromide SCHEMBL5345194 0.92 RAB9A (0.61) CA1CA2CA7CA9CA12
Bromide SCHEMBL5345195 0.92 RAB9A (0.61) CA1CA2CA7CA9CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1991013073-A1 FUNGICIDAL COMPOSITIONS CONTAINING BENZYL-TRIS(ARYL)PHOSPHONIUM SALTS SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) 1991-09-05 WO disclosed