Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 11/20 | 1.00 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.65 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19342750 | 0.89 | PPARG (1.00) | PPARGAGTR1AGTR2 | |
| SCHEMBL9754844 | 0.87 | PPARG (0.78) | PPARGAGTR1AGTR2 | |
| SCHEMBL8396958 | 0.85 | PPARG (1.00) | PPARGAGTR1AGTR2 | |
| SCHEMBL8396606 | 0.83 | AGTR1 (0.75) | PPARGAGTR1AGTR2 | |
| SCHEMBL9336956 | 0.82 | PPARG (0.91) | PPARG | |
| SCHEMBL8395682 | 0.81 | AGTR1 (0.72) | PPARGAGTR1AGTR2 | |
| SCHEMBL29387259 | 0.81 | AGTR1 (0.82) | PPARGAGTR1AGTR2 | |
| SCHEMBL8266757 | 0.81 | AGTR1 (0.82) | PPARGAGTR1AGTR2 | |
| SCHEMBL4569976 | 0.81 | PPARG (0.78) | PPARGAGTR1AGTR2 | |
| SCHEMBL4564619 | 0.81 | PPARG (0.79) | PPARGAGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991013063-A1 | NEW BENZIMIDAZOLE DERIVATIVES, METHOD FOR PREPARING THEM AND THEIR PHARMACEUTICAL USE | SCHERING AKTIENGESELLSCHAFT BERLIN UND BERGKAMEN (DE) | 1991-09-05 | — | — | WO | disclosed |