SCHEMBL9755057

SCHEMBL9755057

NC(CCCc1ccc([N+](=O)[O-])cc1[N+](=O)[O-])C(=O)O

nearest known ligand 0.57

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.57
GRM8 O00222 3/20 0.56
GRM4 Q14833 3/20 0.56
ALDH1A1 P00352 1/20 0.51
TDP1 Q9NUW8 1/20 0.51
PTPRA P18433 1/20 0.48
KMO O15229 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2818968 0.96 CYP1A2 (0.56) CYP1A2GRM8GRM4ALDH1A1TDP1
SCHEMBL1817774 0.85 CYP1A2 (0.61) CYP1A2GRM8GRM4ALDH1A1TDP1
SCHEMBL30959758 0.85 CYP1A2 (0.61) CYP1A2GRM8GRM4ALDH1A1TDP1
SCHEMBL1817775 0.85 CYP1A2 (0.61) CYP1A2GRM8GRM4ALDH1A1TDP1
SCHEMBL31710991 0.82 CYP1A2 (0.53) CYP1A2GRM8GRM4PTPRA
SCHEMBL9116030 0.82 GRM8 (0.63) CYP1A2GRM8GRM4KMO
SCHEMBL21518512 0.82 GRM8 (0.63) CYP1A2GRM8GRM4KMO
SCHEMBL28064736 0.81 CYP1A2 (0.45) CYP1A2GRM8GRM4ALDH1A1TDP1
SCHEMBL3124322 0.80 GRM8 (0.53) GRM8GRM4
SCHEMBL4197255 0.80 CYP1A2 (0.71) CYP1A2ALDH1A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1991005605-A1 CYCLODEXTRIN LABELS FOR IMMUNOASSAY AND BIOCHEMICAL ANALYSIS KOSAK KENNETH M (US) 1991-05-02 WO disclosed