Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 1/20 | 0.63 |
| ▸ | CNR2 | P34972 | 6/20 | 0.58 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.53 |
| ▸ | RAB9A | P51151 | 4/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.53 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.53 |
| ▸ | RELA | Q04206 | 2/20 | 0.53 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | TP53 | P04637 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31378056 | 0.83 | MGAM (0.61) | MGAMCNR2HDAC8ALDH1A1MAPT | |
| SCHEMBL1343443 | 0.79 | CNR2 (0.78) | MGAMCNR2HDAC8ALDH1A1MAPT | |
| SCHEMBL9755296 | 0.79 | MGAM (0.56) | MGAMCNR2HDAC8ALDH1A1MAPT | |
| Quinaldic Acid SCHEMBL29350584 | 0.78 | MGAM (1.00) | MGAMCNR2HDAC8ALDH1A1MAPT | |
| Quinaldic Acid SCHEMBL1242670 | 0.78 | MGAM (1.00) | MGAMCNR2HDAC8ALDH1A1MAPT | |
| SCHEMBL2889584 | 0.78 | MGAM (0.70) | MGAMCNR2HDAC8ALDH1A1MAPT | |
| Quinaldic Acid SCHEMBL39024 | 0.78 | MGAM (1.00) | MGAMCNR2HDAC8ALDH1A1MAPT | |
| Quinaldic Acid SCHEMBL29388807 | 0.77 | MGAM (0.63) | MGAMCNR2HDAC8ALDH1A1MAPT | |
| SCHEMBL409413 | 0.77 | MGAM (0.58) | MGAMCNR2HDAC8ALDH1A1MAPT | |
| SCHEMBL409190 | 0.77 | MGAM (0.58) | MGAMCNR2HDAC8ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991006561-A1 | METHOD FOR TREATING HIV AND OTHER RETROVIRUSES AND COMPOUNDS USEFUL THEREFOR | THE UPJOHN COMPANY (US) | 1991-05-16 | — | — | WO | claimed |
| WO-1991006561-A1 | METHOD FOR TREATING HIV AND OTHER RETROVIRUSES AND COMPOUNDS USEFUL THEREFOR | THE UPJOHN COMPANY (US) | 1991-05-16 | — | — | WO | disclosed |