Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 1/20 | 0.50 |
| ▸ | GGT1 | P19440 | 1/20 | 0.49 |
| ▸ | GSR | P00390 | 1/20 | 0.46 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | CPB2 | Q96IY4 | 8/20 | 0.41 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.40 |
| ▸ | TLR2 | O60603 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.37 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.37 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6859366 | 0.87 | FOLH1 (0.54) | FOLH1GGT1GSRRNPEPMMP2 | |
| SCHEMBL610133 | 0.87 | GGT1 (0.62) | FOLH1GGT1GSRRNPEPMMP2 | |
| SCHEMBL6316197 | 0.87 | FOLH1 (0.54) | FOLH1GGT1GSRRNPEPMMP2 | |
| SCHEMBL610134 | 0.87 | GGT1 (0.62) | FOLH1GGT1GSRRNPEPMMP2 | |
| SCHEMBL148480 | 0.87 | FOLH1 (0.54) | FOLH1GGT1GSRRNPEPMMP2 | |
| SCHEMBL7076576 | 0.87 | FOLH1 (0.54) | FOLH1GGT1GSRRNPEPMMP2 | |
| SCHEMBL31040404 | 0.85 | FOLH1 (0.53) | FOLH1GGT1GSRRNPEPMMP2 | |
| SCHEMBL7196935 | 0.85 | FOLH1 (0.57) | FOLH1GGT1GSRRNPEPMMP2 | |
| SCHEMBL28397660 | 0.85 | FOLH1 (0.53) | FOLH1GGT1GSRRNPEPMMP2 | |
| Hydrochloric Acid SCHEMBL25352316 | 0.84 | FOLH1 (0.51) | FOLH1GGT1GSRRNPEPMMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991005791-A1 | GEM-DIPHOSPHONIC ACIDS, A PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | BOEHRINGER MANNHEIM ITALIA S.P.A. (IT) | 1991-05-02 | — | — | WO | disclosed |