SCHEMBL9755587

SCHEMBL9755587

NCCCN1C(=O)CNC1=O

nearest known ligand 0.47

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.47
GSK3A P49840 1/20 0.43
GSK3B P49841 1/20 0.43
QPCT Q16769 1/20 0.37
HEXA P06865 2/20 0.36
HEXB P07686 2/20 0.36
HTR2A P28223 1/20 0.35
ABL1 P00519 1/20 0.33
LMNA P02545 1/20 0.33
RIN1 Q13671 1/20 0.33
ALDH1A1 P00352 2/20 0.33
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
BRPF1 P55201 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL853544 0.87 TSHR (0.50) TSHRGSK3AGSK3BQPCTHEXA
Hydrochloric Acid SCHEMBL2980753 0.85 TSHR (0.48) TSHRGSK3AGSK3BQPCTHEXA
SCHEMBL7453981 0.79 TSHR (0.47) TSHRGSK3AGSK3BQPCTMEN1
SCHEMBL1401795 0.79 TSHR (0.52) TSHRGSK3AGSK3BQPCTABL1
SCHEMBL10974351 0.79 TSHR (0.47) TSHRGSK3AGSK3BQPCTABL1
SCHEMBL31420563 0.79 TSHR (0.43) TSHRGSK3AGSK3BABL1LMNA
SCHEMBL11483737 0.78
SCHEMBL10976405 0.78 TSHR (0.46) TSHRGSK3AGSK3BQPCTABL1
SCHEMBL14761839 0.78 GSK3A (0.46) TSHRGSK3AGSK3BQPCTABL1
SCHEMBL2991298 0.78 MGLL (0.47) TSHRGSK3AGSK3BALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-3191075-A None JP disclosed
EP-4249492-A1 NOVEL COMPOUND, PREPARATION METHOD THEREOF, AND ANTIBIOTIC COMPOSITION COMPRISING SAME A&J Science Co.,Ltd. (KR) 2023-09-27 EP disclosed
JP-H03191075-A CORROSION INHIBITOR SHOWA DENKO KK 1991-08-21 JP disclosed
US-4073926-A BACTERICIDES, FUNGICIDES GLYCO CHEMICALS, INC. (US) 1978-02-14 US disclosed
US-4073924-A Hydantoin derivatives and broad spectrum bactericidal/fungicidal compositions thereof GLYCO CHEMICALS, INC. (US) 1978-02-14 US disclosed