SCHEMBL9755599

SCHEMBL9755599

NC(=S)NOC(=O)c1ccc(O)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 3/20 0.53
CA1 P00915 3/20 0.53
CA2 P00918 3/20 0.53
CA7 P43166 3/20 0.53
CA9 Q16790 3/20 0.53
CA14 Q9ULX7 3/20 0.53
LMNA P02545 5/20 0.49
ALDH1A1 P00352 3/20 0.49
GAA P10253 1/20 0.49
KDM4E B2RXH2 1/20 0.46
ESR1 P03372 3/20 0.44
KMT2A Q03164 2/20 0.44
MAPT P10636 2/20 0.44
ESR2 Q92731 2/20 0.44
POLB P06746 1/20 0.44
MEN1 O00255 1/20 0.44
PARP10 Q53GL7 1/20 0.44
MPO P05164 1/20 0.44
CYP3A4 P08684 1/20 0.44
KDM5A P29375 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9150262 0.82 ALDH1A1 (0.66) LMNAALDH1A1GAAKDM4EKMT2A
SCHEMBL7051844 0.78 CA12 (0.59) CA12CA1CA2CA7CA9
SCHEMBL27473771 0.74 ALDH1A1 (0.54) CA12CA1CA2CA7CA9
SCHEMBL27356016 0.74 KMT2A (0.82) CA12CA1CA2CA7CA9
Methylparaben SCHEMBL3929092 0.74 CA1 (0.87) CA12CA1CA2CA7CA9
SCHEMBL7555577 0.73 ALDH1A1 (0.52) CA12CA1CA2CA7CA9
Bromide SCHEMBL28362093 0.72 CA1 (0.63) CA12CA1CA2CA7CA9
SCHEMBL29123185 0.72 CA1 (0.67) CA1CA9ALDH1A1GAAKDM4E
SCHEMBL29039142 0.72 HCAR2 (0.42) CA1CA9ALDH1A1KMT2AMAPT
SCHEMBL15706786 0.72 CA12 (0.47) CA12CA1CA2CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1991004781-A1 INSTRUMENT AND METHOD FOR THE LASER DESORPTION OF IONS IN MASS SPECTROMETRY THE ROCKEFELLER UNIVERSITY (US) 1991-04-18 WO disclosed