Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MIF | P14174 | 2/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9522182 | 0.89 | MIF (0.41) | ADRA1ACYP1A2ACHEMIFMTNR1A | |
| SCHEMBL8903352 | 0.87 | MIF (0.42) | ADRA1ACYP1A2ACHEHTTMIF | |
| SCHEMBL8903292 | 0.84 | ADRA1A (0.41) | ADRA1ACYP1A2PDE4APDE4BPDE4C | |
| SCHEMBL8901652 | 0.81 | CYP1A2 (0.39) | ADRA1ACYP1A2PDE4APDE4BPDE4C | |
| SCHEMBL8529148 | 0.73 | ADRA1A (0.39) | ADRA1AACHEHPGDGAAKDM4E | |
| SCHEMBL8527470 | 0.73 | CYP1A2 (0.47) | ADRA1ACYP1A2PDE4APDE4BPDE4C | |
| SCHEMBL8528137 | 0.72 | MIF (0.42) | ADRA1ACYP1A2ACHEMIFMTNR1A | |
| SCHEMBL8901958 | 0.72 | ADRA1A (0.41) | ADRA1AACHE | |
| SCHEMBL8901795 | 0.71 | MIF (0.43) | ADRA1ACYP1A2ACHEHTTMIF | |
| SCHEMBL8903651 | 0.71 | ADRA1A (0.40) | ADRA1AACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991019725-A2 | HETEROCYCLIC ANTHRACYCLIONE AND ANTHRACYCLINE ANALOGS | BIOCHEM PHARMA INC. (CA) | 1991-12-26 | — | — | WO | disclosed |