Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 4/20 | 0.49 |
| ▸ | MMP8 | P22894 | 1/20 | 0.47 |
| ▸ | CTSS | P25774 | 2/20 | 0.46 |
| ▸ | CTSK | P43235 | 2/20 | 0.46 |
| ▸ | CTSL | P07711 | 1/20 | 0.46 |
| ▸ | CTSB | P07858 | 1/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 2/20 | 0.45 |
| ▸ | PPARD | Q03181 | 2/20 | 0.45 |
| ▸ | PPARA | Q07869 | 2/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | MME | P08473 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9755821 | 1.00 | ANPEP (0.49) | ANPEPMMP8CTSSCTSKCTSL | |
| SCHEMBL9755811 | 0.84 | MDM2 (0.50) | CTSSCTSKCTSLCTSBMCL1 | |
| SCHEMBL1442737 | 0.82 | MMP8 (0.58) | MMP8PPARGPPARDPPARAATM | |
| SCHEMBL5452680 | 0.81 | MMP8 (0.55) | MMP8PPARGPPARDPPARAATM | |
| SCHEMBL391783 | 0.81 | PPARG (0.61) | MMP8PPARGPPARDPPARAATM | |
| SCHEMBL8287672 | 0.81 | PPARG (0.61) | MMP8PPARGPPARDPPARAATM | |
| SCHEMBL5143613 | 0.80 | MMP8 (0.50) | MMP8PPARGPPARDPPARAATM | |
| SCHEMBL7270701 | 0.79 | MMP8 (0.55) | MMP8PPARGPPARDPPARAATM | |
| SCHEMBL1259770 | 0.78 | MMP8 (0.54) | MMP8PPARGPPARDPPARAATM | |
| SCHEMBL9755276 | 0.77 | ATM (0.59) | ANPEPCTSSCTSLCTSBATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991005763-A1 | DIPEPTIDE-ANALOG-BASED METALLOENDOPEPTIDASE INHIBITORS AND METHODS OF USING SAME | THE SALK INSTITUTE BIOTECHNOLOGY/INDUSTRIAL ASSOCIATES, INC. (US) | 1991-05-02 | — | — | WO | disclosed |