Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 5/20 | 0.67 |
| ▸ | LTA4H | P09960 | 3/20 | 0.55 |
| ▸ | ANPEP | P15144 | 1/20 | 0.52 |
| ▸ | ECE1 | P42892 | 1/20 | 0.52 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | ACE | P12821 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9755802 | 0.89 | MME (0.76) | MMELTA4HANPEPECE1ACE | |
| SCHEMBL9755813 | 0.88 | MME (0.78) | MMEANPEPBIRC2 | |
| SCHEMBL9755830 | 0.87 | BIRC2 (0.70) | MMEANPEPBIRC2 | |
| SCHEMBL9755834 | 0.81 | MME (1.00) | MMEACE | |
| SCHEMBL9755824 | 0.81 | MME (0.80) | MMELTA4HECE1BIRC2 | |
| SCHEMBL9755806 | 0.80 | MME (0.62) | MMEECE1MAPTACE | |
| SCHEMBL9755796 | 0.77 | MME (0.71) | MMEANPEP | |
| SCHEMBL9755800 | 0.77 | MME (0.71) | MMEANPEP | |
| SCHEMBL9755807 | 0.77 | MME (0.67) | MMEECE1MAPTACE | |
| SCHEMBL9755809 | 0.77 | MME (0.67) | MMEECE1MAPTACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991005763-A1 | DIPEPTIDE-ANALOG-BASED METALLOENDOPEPTIDASE INHIBITORS AND METHODS OF USING SAME | THE SALK INSTITUTE BIOTECHNOLOGY/INDUSTRIAL ASSOCIATES, INC. (US) | 1991-05-02 | — | — | WO | disclosed |