Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 6/20 | 0.67 |
| ▸ | ACE | P12821 | 3/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | ECE1 | P42892 | 1/20 | 0.60 |
| ▸ | BLM | P54132 | 1/20 | 0.60 |
| ▸ | NPEPPS | P55786 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | CTSL | P07711 | 1/20 | 0.45 |
| ▸ | CTSS | P25774 | 1/20 | 0.45 |
| ▸ | CTSK | P43235 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9755807 | 1.00 | MME (0.67) | MMEACEALDH1A1HPGDMAPK1 | |
| SCHEMBL9755806 | 0.88 | MME (0.62) | MMEACEALDH1A1HPGDMAPK1 | |
| SCHEMBL9755796 | 0.82 | MME (0.71) | MME | |
| SCHEMBL9755800 | 0.82 | MME (0.71) | MME | |
| SCHEMBL10447979 | 0.81 | MME (0.81) | MMEACEALDH1A1HPGDMAPK1 | |
| SCHEMBL9755834 | 0.81 | MME (1.00) | MMEACE | |
| SCHEMBL9755802 | 0.80 | MME (0.76) | MMEACEECE1 | |
| SCHEMBL7325845 | 0.78 | MME (1.00) | MMEACEALDH1A1HPGDMAPK1 | |
| SCHEMBL7325851 | 0.78 | MME (1.00) | MMEACEALDH1A1HPGDMAPK1 | |
| SCHEMBL7325857 | 0.78 | MME (1.00) | MMEACEALDH1A1HPGDMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991005763-A1 | DIPEPTIDE-ANALOG-BASED METALLOENDOPEPTIDASE INHIBITORS AND METHODS OF USING SAME | THE SALK INSTITUTE BIOTECHNOLOGY/INDUSTRIAL ASSOCIATES, INC. (US) | 1991-05-02 | — | — | WO | disclosed |