Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | DHODH | Q02127 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.36 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28601258 | 0.75 | KDM4E (0.39) | NPC1RAB9ALMNAPDE10AALDH1A1 | |
| SCHEMBL14462712 | 0.71 | NPC1 (0.50) | NPC1RAB9ALMNAALDH1A1PPARG | |
| SCHEMBL26922384 | 0.71 | NPC1 (0.50) | NPC1RAB9ALMNAALDH1A1PPARG | |
| SCHEMBL841683 | 0.69 | CYP3A4 (0.45) | ALDH1A1TSHRKDM4ETHRBMAPT | |
| SCHEMBL28300794 | 0.69 | NPC1 (0.47) | NPC1RAB9ALMNAALDH1A1KDM4E | |
| SCHEMBL17296033 | 0.69 | NPC1 (0.51) | NPC1RAB9ALMNAALDH1A1KDM4E | |
| SCHEMBL28695407 | 0.69 | NPC1 (0.44) | NPC1RAB9ALMNAPDE10AALDH1A1 | |
| SCHEMBL673476 | 0.69 | NPC1 (0.38) | NPC1RAB9ALMNAALDH1A1PPARG | |
| SCHEMBL11758333 | 0.68 | NPC1 (0.54) | NPC1RAB9ALMNAALDH1A1PPARG | |
| SCHEMBL26922499 | 0.68 | NPC1 (0.50) | NPC1RAB9ALMNAALDH1A1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-3200788-A | — | — | None | — | — | JP | disclosed |
| JP-H03200788-A | BENZOTRIAZOLE-BASED COMPOUND AND USE THEREOF | KURARAY CO LTD | 1991-09-02 | — | — | JP | disclosed |