Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.54 |
| ▸ | RAB9A | P51151 | 4/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | STAT3 | P40763 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26922499 | 0.86 | NPC1 (0.50) | NPC1RAB9ALMNAPOLBALDH1A1 | |
| SCHEMBL14462716 | 0.80 | NPC1 (0.50) | NPC1RAB9ALMNAPOLBALDH1A1 | |
| SCHEMBL14462712 | 0.79 | NPC1 (0.50) | NPC1RAB9ALMNAPOLBALDH1A1 | |
| SCHEMBL1931323 | 0.79 | RAB9A (0.49) | NPC1RAB9ALMNAPOLBALDH1A1 | |
| SCHEMBL26922384 | 0.76 | NPC1 (0.50) | NPC1RAB9ALMNAPOLBALDH1A1 | |
| SCHEMBL110113 | 0.76 | NPC1 (0.71) | NPC1RAB9ALMNAPOLBALDH1A1 | |
| SCHEMBL29489567 | 0.76 | NPC1 (0.71) | NPC1RAB9ALMNAPOLBALDH1A1 | |
| SCHEMBL1275936 | 0.76 | NPC1 (0.71) | NPC1RAB9ALMNAPOLBALDH1A1 | |
| SCHEMBL2474061 | 0.76 | RAB9A (0.49) | NPC1RAB9ALMNAPOLBALDH1A1 | |
| SCHEMBL2802927 | 0.76 | NPC1 (0.49) | NPC1RAB9ALMNAPOLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4065427-A | Polychromophoric heterocyclic ultraviolet stabilizers and their use in organic compositions | EASTMAN KODAK COMPANY (US) | 1977-12-27 | — | — | US | disclosed |
| US-4000148-A | POLYMERS | EASTMAN KODAK COMPANY (US) | 1976-12-28 | — | — | US | disclosed |