Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 18/20 | 0.65 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.62 |
| ▸ | MT-CO1 | P00395 | 1/20 | 0.62 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.62 |
| ▸ | HPGD | P15428 | 1/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8985270 | 0.85 | PTGS2 (0.69) | PTGS2PTGS1KDM4EMT-CO1MT-CO2 | |
| SCHEMBL8985504 | 0.82 | PTGS2 (0.66) | PTGS2PTGS1KDM4EMT-CO1MT-CO2 | |
| SCHEMBL8985438 | 0.79 | PTGS2 (0.72) | PTGS2PTGS1KDM4EMT-CO1MT-CO2 | |
| SCHEMBL3253233 | 0.79 | PTGS2 (1.00) | PTGS2PTGS1KDM4EMT-CO1MT-CO2 | |
| SCHEMBL8097094 | 0.77 | PTGS2 (0.70) | PTGS2PTGS1KDM4EMT-CO1MT-CO2 | |
| SCHEMBL8985297 | 0.77 | PTGS2 (0.73) | PTGS2PTGS1KDM4EMT-CO1MT-CO2 | |
| SCHEMBL8985305 | 0.77 | PTGS2 (0.69) | PTGS2PTGS1KDM4EMT-CO1MT-CO2 | |
| SCHEMBL8985515 | 0.77 | PTGS2 (1.00) | PTGS2PTGS1KDM4EMT-CO1MT-CO2 | |
| Dup-697 SCHEMBL1041241 | 0.77 | PTGS2 (1.00) | PTGS2PTGS1KDM4EMT-CO1MT-CO2 | |
| SCHEMBL10567845 | 0.77 | PTGS2 (1.00) | PTGS2PTGS1KDM4EMT-CO1MT-CO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991019708-A1 | NEW THIOPHENE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-12-26 | — | — | WO | disclosed |