Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9756229 | 0.89 | ABCB1 (0.42) | HDAC1ABCB1 | |
| SCHEMBL9755896 | 0.89 | ALDH1A1 (0.48) | HDAC8HDAC1ALDH1A1MAPK1 | |
| SCHEMBL9756326 | 0.88 | HDAC8 (0.49) | HDAC8HDAC1 | |
| SCHEMBL9756293 | 0.87 | ABCB1 (0.42) | HDAC8HDAC1ABCB1 | |
| SCHEMBL9755946 | 0.87 | HDAC8 (0.51) | HDAC8HDAC1 | |
| SCHEMBL9756125 | 0.87 | HDAC8 (0.51) | HDAC8HDAC1 | |
| SCHEMBL9756087 | 0.87 | HDAC8 (0.51) | HDAC8HDAC1 | |
| SCHEMBL9756188 | 0.87 | HDAC8 (0.51) | HDAC8HDAC1 | |
| SCHEMBL9756022 | 0.87 | HDAC8 (0.51) | HDAC8HDAC1 | |
| SCHEMBL9756008 | 0.86 | MAPT (0.46) | ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0234944-B1 | INSECTICIDAL N'-SUBSTITUTED-N-ACYL-N'-ALKYLCARBONYLHYDRAZINES | ROHM AND HAAS COMPANY (US) | 1991-04-10 | — | — | EP | disclosed |
| EP-0232075-B1 | INSECTICIDAL N'-SUBSTITUTED-N-ALKYLCARBONYL-N'-ACYL HYDRAZINES | ROHM AND HAAS COMPANY (US) | 1991-03-13 | — | — | EP | disclosed |
| EP-0232075-A1 | Insecticidal N'-substituted-N-alkylcarbonyl-N'-acyl hydrazines | ROHM AND HAAS COMPANY (US) | 1987-08-12 | — | — | EP | disclosed |