Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9756358 | 0.91 | CYP3A4 (0.45) | ABCB1CYP3A4CYP2C9NPC1HTT | |
| SCHEMBL9755936 | 0.89 | ABCB1 (0.42) | ABCB1CYP3A4CYP2C9NPC1HTT | |
| SCHEMBL9756100 | 0.88 | ABCB1 (0.58) | ABCB1CYP3A4CYP2C9HDAC6POLB | |
| SCHEMBL9756044 | 0.87 | ABCB1 (0.48) | ABCB1CYP3A4CYP2C9NPC1HTT | |
| SCHEMBL9756322 | 0.86 | POLB (0.56) | CYP3A4CYP2C9POLBSMN1; SMN2 | |
| SCHEMBL9756092 | 0.85 | CYP3A4 (0.44) | ABCB1CYP3A4CYP2C9NPC1HTT | |
| SCHEMBL9756336 | 0.84 | CYP3A4 (0.52) | ABCB1CYP3A4CYP2C9NPC1HTT | |
| SCHEMBL9756419 | 0.84 | HDAC1 (0.44) | ABCB1CYP3A4CYP2C9NPC1HTT | |
| SCHEMBL9755975 | 0.83 | CYP3A4 (0.49) | ABCB1CYP3A4CYP2C9NPC1HTT | |
| SCHEMBL9755929 | 0.82 | CYP3A4 (0.46) | ABCB1CYP3A4CYP2C9POLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0234944-B1 | INSECTICIDAL N'-SUBSTITUTED-N-ACYL-N'-ALKYLCARBONYLHYDRAZINES | ROHM AND HAAS COMPANY (US) | 1991-04-10 | — | — | EP | disclosed |
| EP-0232075-B1 | INSECTICIDAL N'-SUBSTITUTED-N-ALKYLCARBONYL-N'-ACYL HYDRAZINES | ROHM AND HAAS COMPANY (US) | 1991-03-13 | — | — | EP | disclosed |
| EP-0234944-A1 | Insecticidal N'-substituted-N-acyl-N'-alkylcarbonylhydrazines | ROHM AND HAAS COMPANY (US) | 1987-09-02 | — | — | EP | disclosed |