Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 5/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9756358 | 0.89 | CYP3A4 (0.45) | ABCB1CYP3A4CYP2C9HDAC1HDAC6 | |
| SCHEMBL9755931 | 0.87 | ABCB1 (0.43) | ABCB1CYP3A4CYP2C9HDAC1HDAC6 | |
| SCHEMBL9755954 | 0.87 | ABCB1 (0.65) | ABCB1CYP3A4CYP2C9HDAC6 | |
| SCHEMBL9756119 | 0.85 | POLB (0.60) | CYP3A4CYP2C9POLB | |
| SCHEMBL9756336 | 0.85 | CYP3A4 (0.52) | ABCB1CYP3A4CYP2C9HDAC1HDAC6 | |
| SCHEMBL9755975 | 0.81 | CYP3A4 (0.49) | ABCB1CYP3A4CYP2C9HDAC1HDAC6 | |
| SCHEMBL9756043 | 0.81 | CYP3A4 (0.49) | ABCB1CYP3A4CYP2C9POLB | |
| SCHEMBL9756419 | 0.81 | HDAC1 (0.44) | ABCB1CYP3A4CYP2C9HDAC1HDAC6 | |
| SCHEMBL9756540 | 0.80 | CYP3A4 (0.47) | ABCB1CYP3A4CYP2C9HDAC1HDAC6 | |
| SCHEMBL9756460 | 0.80 | CYP3A4 (0.47) | ABCB1CYP3A4CYP2C9HDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0234944-B1 | INSECTICIDAL N'-SUBSTITUTED-N-ACYL-N'-ALKYLCARBONYLHYDRAZINES | ROHM AND HAAS COMPANY (US) | 1991-04-10 | — | — | EP | disclosed |
| EP-0232075-B1 | INSECTICIDAL N'-SUBSTITUTED-N-ALKYLCARBONYL-N'-ACYL HYDRAZINES | ROHM AND HAAS COMPANY (US) | 1991-03-13 | — | — | EP | disclosed |