Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9755987 | 0.96 | HPGD (0.44) | HPGDSMN1; SMN2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL9756439 | 0.95 | HPGD (0.43) | HPGDSMN1; SMN2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL9756099 | 0.93 | SMN1; SMN2 (0.47) | HPGDSMN1; SMN2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL9755978 | 0.88 | POLB (0.55) | HPGDSMN1; SMN2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL9756433 | 0.88 | SMN1; SMN2 (0.49) | HPGDSMN1; SMN2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL9755951 | 0.84 | POLB (0.53) | HPGDSMN1; SMN2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL9756455 | 0.83 | POLB (0.52) | HPGDSMN1; SMN2CYP3A4CYP2C9POLB | |
| SCHEMBL9755960 | 0.81 | HPGD (0.45) | HPGDSMN1; SMN2ABCB1 | |
| SCHEMBL9756062 | 0.81 | ABCB1 (0.54) | HPGDCYP3A4CYP2C9ABCB1 | |
| SCHEMBL9756013 | 0.80 | POLB (0.57) | HPGDSMN1; SMN2CYP3A4CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0234944-B1 | INSECTICIDAL N'-SUBSTITUTED-N-ACYL-N'-ALKYLCARBONYLHYDRAZINES | ROHM AND HAAS COMPANY (US) | 1991-04-10 | — | — | EP | disclosed |
| EP-0232075-B1 | INSECTICIDAL N'-SUBSTITUTED-N-ALKYLCARBONYL-N'-ACYL HYDRAZINES | ROHM AND HAAS COMPANY (US) | 1991-03-13 | — | — | EP | disclosed |
| EP-0232075-A1 | Insecticidal N'-substituted-N-alkylcarbonyl-N'-acyl hydrazines | ROHM AND HAAS COMPANY (US) | 1987-08-12 | — | — | EP | disclosed |