Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9755951 | 0.96 | POLB (0.53) | POLBSMN1; SMN2CYP3A4CYP2C9RECQL | |
| SCHEMBL9756455 | 0.95 | POLB (0.52) | POLBSMN1; SMN2CYP3A4CYP2C9RECQL | |
| SCHEMBL9756013 | 0.92 | POLB (0.57) | POLBSMN1; SMN2CYP3A4CYP2C9RECQL | |
| SCHEMBL9755958 | 0.88 | HPGD (0.45) | POLBSMN1; SMN2CYP3A4CYP2C9HPGD | |
| SCHEMBL9756062 | 0.87 | ABCB1 (0.54) | CYP3A4CYP2C9HPGD | |
| SCHEMBL9755877 | 0.87 | POLB (0.60) | POLBSMN1; SMN2CYP3A4CYP2C9RECQL | |
| SCHEMBL9756376 | 0.86 | CYP3A4 (0.45) | POLBSMN1; SMN2CYP3A4CYP2C9RECQL | |
| SCHEMBL9755987 | 0.84 | HPGD (0.44) | POLBSMN1; SMN2CYP3A4CYP2C9HPGD | |
| SCHEMBL9756372 | 0.84 | ABCB1 (0.53) | CYP3A4CYP2C9HPGD | |
| SCHEMBL9756439 | 0.83 | HPGD (0.43) | SMN1; SMN2CYP3A4CYP2C9HPGDHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0234944-B1 | INSECTICIDAL N'-SUBSTITUTED-N-ACYL-N'-ALKYLCARBONYLHYDRAZINES | ROHM AND HAAS COMPANY (US) | 1991-04-10 | — | — | EP | disclosed |
| EP-0232075-B1 | INSECTICIDAL N'-SUBSTITUTED-N-ALKYLCARBONYL-N'-ACYL HYDRAZINES | ROHM AND HAAS COMPANY (US) | 1991-03-13 | — | — | EP | disclosed |