Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9755981 | 0.92 | POLB (0.55) | POLBCYP3A4CYP2C9 | |
| SCHEMBL9755955 | 0.91 | POLB (0.53) | POLBCYP3A4CYP2C9 | |
| SCHEMBL9756458 | 0.90 | POLB (0.52) | POLBCYP3A4CYP2C9 | |
| SCHEMBL9755882 | 0.89 | POLB (0.60) | POLBCYP3A4CYP2C9HPGDSMN1; SMN2 | |
| SCHEMBL9756101 | 0.87 | HPGD (0.47) | CYP3A4HPGDSMN1; SMN2 | |
| SCHEMBL9756104 | 0.87 | ABCB1 (0.59) | POLBCYP3A4CYP2C9 | |
| SCHEMBL9756092 | 0.86 | CYP3A4 (0.44) | POLBCYP3A4CYP2C9SMN1; SMN2 | |
| SCHEMBL9756322 | 0.83 | POLB (0.56) | POLBCYP3A4CYP2C9HPGDSMN1; SMN2 | |
| SCHEMBL9755883 | 0.81 | POLB (0.53) | POLBCYP3A4CYP2C9 | |
| SCHEMBL9756141 | 0.81 | CTSD (0.46) | HPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0234944-B1 | INSECTICIDAL N'-SUBSTITUTED-N-ACYL-N'-ALKYLCARBONYLHYDRAZINES | ROHM AND HAAS COMPANY (US) | 1991-04-10 | — | — | EP | disclosed |
| EP-0232075-B1 | INSECTICIDAL N'-SUBSTITUTED-N-ALKYLCARBONYL-N'-ACYL HYDRAZINES | ROHM AND HAAS COMPANY (US) | 1991-03-13 | — | — | EP | disclosed |
| EP-0234944-A1 | Insecticidal N'-substituted-N-acyl-N'-alkylcarbonylhydrazines | ROHM AND HAAS COMPANY (US) | 1987-09-02 | — | — | EP | disclosed |