Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSD | P07339 | 1/20 | 0.47 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9756127 | 1.00 | CTSD (0.47) | CTSDABCB1HDAC8HDAC1ALDH1A1 | |
| SCHEMBL9756193 | 1.00 | CTSD (0.47) | CTSDABCB1HDAC8HDAC1ALDH1A1 | |
| SCHEMBL9756089 | 1.00 | CTSD (0.47) | CTSDABCB1HDAC8HDAC1ALDH1A1 | |
| SCHEMBL9755948 | 1.00 | CTSD (0.47) | CTSDABCB1HDAC8HDAC1ALDH1A1 | |
| SCHEMBL9756329 | 0.99 | CTSD (0.48) | CTSDABCB1ALDH1A1MAPK1MAPT | |
| SCHEMBL9756462 | 0.95 | CTSD (0.49) | CTSDABCB1ALDH1A1MAPK1MAPT | |
| SCHEMBL9756010 | 0.90 | CTSD (0.51) | CTSDABCB1MAPK1MAPTSMN1; SMN2 | |
| SCHEMBL9755905 | 0.87 | CTSD (0.43) | CTSDABCB1ALDH1A1MAPK1MAPT | |
| SCHEMBL9756349 | 0.86 | CTSD (0.55) | CTSDABCB1MAPK1MAPTSMN1; SMN2 | |
| SCHEMBL9756050 | 0.86 | HPGD (0.49) | CTSDABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0234944-B1 | INSECTICIDAL N'-SUBSTITUTED-N-ACYL-N'-ALKYLCARBONYLHYDRAZINES | ROHM AND HAAS COMPANY (US) | 1991-04-10 | — | — | EP | disclosed |
| EP-0232075-B1 | INSECTICIDAL N'-SUBSTITUTED-N-ALKYLCARBONYL-N'-ACYL HYDRAZINES | ROHM AND HAAS COMPANY (US) | 1991-03-13 | — | — | EP | disclosed |
| EP-0234944-A1 | Insecticidal N'-substituted-N-acyl-N'-alkylcarbonylhydrazines | ROHM AND HAAS COMPANY (US) | 1987-09-02 | — | — | EP | disclosed |