Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9756202 | 0.85 | POLB (0.67) | CYP3A4CYP2C9CYP2C19HTTPOLB | |
| SCHEMBL9755970 | 0.83 | CYP3A4 (0.47) | CYP3A4CYP2C9CYP2C19HTTPOLB | |
| SCHEMBL9756135 | 0.81 | CYP3A4 (0.53) | CYP3A4CYP2C9CYP2C19HTTPOLB | |
| SCHEMBL9714227 | 0.81 | POLB (0.71) | CYP3A4CYP2C9POLBHPGDSMN1; SMN2 | |
| SCHEMBL9756155 | 0.81 | HTT (0.45) | CYP3A4CYP2C9CYP2C19HTTPOLB | |
| SCHEMBL9756433 | 0.81 | SMN1; SMN2 (0.49) | CYP3A4CYP2C9CYP2C19HTTPOLB | |
| SCHEMBL9756099 | 0.79 | SMN1; SMN2 (0.47) | CYP3A4CYP2C9CYP2C19HTTPOLB | |
| SCHEMBL9756082 | 0.78 | POLB (0.50) | CYP3A4CYP2C9CYP2C19HTTPOLB | |
| SCHEMBL9756219 | 0.78 | HPGD (0.58) | CYP3A4CYP2C9CYP2C19HTTPOLB | |
| SCHEMBL9755958 | 0.77 | HPGD (0.45) | CYP3A4CYP2C9CYP2C19HTTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0234944-B1 | INSECTICIDAL N'-SUBSTITUTED-N-ACYL-N'-ALKYLCARBONYLHYDRAZINES | ROHM AND HAAS COMPANY (US) | 1991-04-10 | — | — | EP | disclosed |
| EP-0232075-A1 | Insecticidal N'-substituted-N-alkylcarbonyl-N'-acyl hydrazines | ROHM AND HAAS COMPANY (US) | 1987-08-12 | — | — | EP | disclosed |