Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.45 |
| ▸ | RELA | Q04206 | 1/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9756004 | 0.96 | SMN1; SMN2 (0.49) | SMN1; SMN2POLBHDAC3HDAC1HDAC2 | |
| SCHEMBL9756118 | 0.93 | SMN1; SMN2 (0.52) | SMN1; SMN2POLBALDH1A1MAPTHPGD | |
| SCHEMBL9755939 | 0.92 | HDAC3 (0.51) | SMN1; SMN2POLBHDAC3HDAC1HDAC2 | |
| SCHEMBL9756166 | 0.91 | SMN1; SMN2 (0.59) | SMN1; SMN2POLBHDAC3HDAC1HDAC2 | |
| SCHEMBL9756112 | 0.90 | HDAC3 (0.55) | SMN1; SMN2HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL9756018 | 0.88 | SMN1; SMN2 (0.57) | SMN1; SMN2POLBHDAC1HDAC2 | |
| SCHEMBL9755966 | 0.85 | SMN1; SMN2 (0.54) | SMN1; SMN2POLBMAPTHPGD | |
| SCHEMBL9756353 | 0.84 | HPGD (0.50) | SMN1; SMN2POLBALDH1A1HPGD | |
| SCHEMBL9755903 | 0.83 | POLB (0.61) | SMN1; SMN2POLBHDAC1HDAC2HDAC8 | |
| SCHEMBL9756425 | 0.83 | ALDH1A1 (0.52) | SMN1; SMN2POLBALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0234944-B1 | INSECTICIDAL N'-SUBSTITUTED-N-ACYL-N'-ALKYLCARBONYLHYDRAZINES | ROHM AND HAAS COMPANY (US) | 1991-04-10 | — | — | EP | disclosed |
| EP-0232075-B1 | INSECTICIDAL N'-SUBSTITUTED-N-ALKYLCARBONYL-N'-ACYL HYDRAZINES | ROHM AND HAAS COMPANY (US) | 1991-03-13 | — | — | EP | disclosed |
| EP-0232075-A1 | Insecticidal N'-substituted-N-alkylcarbonyl-N'-acyl hydrazines | ROHM AND HAAS COMPANY (US) | 1987-08-12 | — | — | EP | disclosed |