Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8173866 | 0.89 | ABCB1 (0.57) | POLBCYP3A4CYP2C9SMN1; SMN2CYP2C19 | |
| SCHEMBL9756009 | 0.84 | POLB (0.63) | POLBCYP3A4CYP2C9SMN1; SMN2RECQL | |
| SCHEMBL9756369 | 0.82 | POLB (0.60) | POLBCYP3A4CYP2C9SMN1; SMN2RECQL | |
| SCHEMBL9755877 | 0.82 | POLB (0.60) | POLBCYP3A4CYP2C9SMN1; SMN2RECQL | |
| SCHEMBL9756202 | 0.81 | POLB (0.67) | POLBCYP3A4CYP2C9SMN1; SMN2RECQL | |
| SCHEMBL8426425 | 0.80 | POLB (0.75) | POLBCYP3A4CYP2C9SMN1; SMN2RECQL | |
| SCHEMBL9756013 | 0.80 | POLB (0.57) | POLBCYP3A4CYP2C9SMN1; SMN2RECQL | |
| SCHEMBL9755978 | 0.78 | POLB (0.55) | POLBCYP3A4CYP2C9SMN1; SMN2RECQL | |
| SCHEMBL10773061 | 0.77 | POLB (0.61) | POLBCYP3A4CYP2C9NPSR1 | |
| Rh-5849 SCHEMBL1538531 | 0.77 | POLB (1.00) | POLBCYP3A4CYP2C9SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0347216-A2 | Insecticidal N'-substituted-N-alkylcarbonyl-N'-acylhydrazines and N'-substituted -N-acyl-N'-alkylcarbonyl hydrazines | ROHM AND HAAS COMPANY (US) | 1989-12-20 | — | — | EP | claimed |
| EP-0234944-B1 | INSECTICIDAL N'-SUBSTITUTED-N-ACYL-N'-ALKYLCARBONYLHYDRAZINES | ROHM AND HAAS COMPANY (US) | 1991-04-10 | — | — | EP | disclosed |